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Telethon Kids Cancer Centre Director

W. Joost Lesterhuis


NHMRC Early Career Investigator

Head of Sarcoma Translational Research

The focus of the Oncogenic Signalling Laboratory is the identification and characterisation of cellular networks that promote the survival and/or growth of cancer cells, especially brain cancer. This knowledge is then used to develop novel therapeutic strategies.

Researchers in the Sarcoma Translational Research Team aim to identify new treatments for children with sarcoma using a multidisciplinary approach combining cancer biology, immunology, systems biology and drug discovery.

We strive for a future where no child will die from brain cancer because we have developed new therapies that will cure their disease.

The main aim of our Leukaemia Translational Research Team is to test innovative therapeutic approaches, with a focus on clinical translation of this knowledge, to improve the outcomes of children suffering from leukaemia.

The Translational Genomics in Leukaemia team is focused on identifying the causes of leukaemia, with the goal of developing new targeted treatments to improve quality of care and long-term survival for all children with leukaemia.

The research of the Cancer Immunotherapy and Neuroblastoma group is focused on harnessing the power of the immune system to eradicate childhood cancer, with a particular focus on neuroblastoma.

Preclinical Paediatric Cancer

The Preclinical Paediatric Cancer group works accross all of the other teams to help facilitate and coordinate our collaborative research efforts.

Cancer Centre Support

The Cancer Centre Support team ensures the daily operations of the Cancer Centre run smoothy, freeing up our team members to focus on their vital research.